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Updated: Jun 5, 2025

EPR Monitored Redox Titration of the Cofactors of Saccharomyces cerevisiae Nar1
Published on: November 26, 2014
Mushroom-Mediated Redox Reactions
1State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, 730000, Lanzhou, China.
Abstract:
The application of biocatalysts in organic synthesis has grown significantly in recent years, and both academia and industry are continuously searching for novel biocatalysts capable of performing challenging chemical reactions. Mushrooms are a rich source of ligninolytic and secondary metabolite biosynthetic enzymes, and therefore were considered promising biocatalysts for organic synthesis. This review focuses on the broad utilization potential of mushroom-based biocatalysts and highlights key advances in mushroom-mediated redox reactions. It mainly includes the reduction of ketones and carboxylic acids, hydroxylation of aromatic and aliphatic compounds, epoxidation of olefins, oxidative cleavage of alkenes, and other uncommon reactions catalyzed by the whole cells or purified enzymes of mushroom origin. Overall, a comprehensive overview of the applications of mushrooms as biocatalysts in organic synthesis is provided, which puts this versatile microorganism in the spotlight of further research.
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