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Adult Intussusception in Jordan: Demographics, Clinical Features, and Outcomes from a Tertiary Hospital
Ruba A Khasawneh1, Yousef Saleh Khader2, Maha Mohamed Gharaibeh1
1Department of Diagnostic Radiology and Nuclear Medicine, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan.
Adult intussusception (AI) is rare, often affecting the colon. Bleeding per rectum is a key indicator of potential malignant lead points, necessitating a multidisciplinary approach for effective management.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Radiology
Background:
- Adult intussusception (AI) is a rare condition with varied presentations.
- Understanding AI epidemiology and distinguishing benign from malignant lead points is critical for management.
- This study investigates AI characteristics and factors predicting malignant lead points.
Purpose of the Study:
- To assess demographic and clinical features of pathological AI.
- To identify predictive factors for malignant lead points in adult intussusception.
- To analyze the association between clinical presentation and etiology in AI.
Main Methods:
- Retrospective analysis of 26 adult AI cases (2014-2024).
- Classification by intussusception location and etiology.
- Assessment of predictive factors including age, sex, symptoms, location, size; CT scan review.
- Exclusion of transient and feeding tube-related intussusceptions.
Main Results:
- AI predominantly affects males (69.2%), mean age 53.3 years.
- Colocolic intussusception is most common (53.8%); surgery is frequent (69.2%).
- Benign lead points (lipomas, polyps) found in 57.7%; bleeding per rectum linked to malignancy (P=0.011).
Conclusions:
- AI presents diversely, predominantly affecting the colon.
- Bleeding per rectum is a significant predictor of malignant lead points in AI.
- A multidisciplinary approach is vital for optimal AI management.
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