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Two-dimensional nanostructures based '-onics' and '-omics' in personalized medicine
Bibi Mary Francis1, Aravindkumar Sundaram2, Rajesh Kumar Manavalan2
1Center for Advanced Materials, Aaivalayam-DIRAC Institute, Coimbatore, Tamil Nadu, India.
Nanophotonics (Berlin, Germany)
|December 5, 2024
Summary
Advanced two-dimensional (2D) materials are enabling personalized, decentralized biomedical devices. Their unique properties enhance photonics/electronics and genomics/exposomics for precise, low-cost medical applications at the point-of-care.
Area of Science:
- Materials Science, Nanotechnology, Biomedical Engineering
- Focus on advanced synthesis and engineering of two-dimensional (2D) materials and their nanostructures.
- Exploration of nanocomposites, hybrid nanostructures, alloys, and heterostructures for novel functionalities.
Background:
- Biomedical devices are increasingly trending towards decentralization and personalization with high precision.
- Unique properties of 2D materials like high surface-to-volume ratio, active sites, tunable bandgap, nonlinear optical properties, and high carrier mobility are crucial.
- These properties are advantageous for 'onics' (photonics/electronics) and 'omics' (genomics/exposomics) technologies.
Purpose of the Study:
- To review developments in point-of-care (POC) technology.
- To examine the application of 'onics' and 'omics' in POC medicine.
- To highlight the role of two-dimensional materials in advancing these technologies.
Main Methods:
- Literature review focusing on advancements in 2D materials synthesis and engineering.
- Analysis of the integration of 2D materials into biomedical devices.
- Discussion of photonic and electronic device applications in personalized medicine.
Main Results:
- 2D materials offer unique properties suitable for advanced biomedical applications.
- Significant progress has been made in developing 2D material-based devices for POC diagnostics.
- The review covers prospects for photonic devices and discusses electronic devices for personalized medicine.
Conclusions:
- Two-dimensional materials are pivotal in developing next-generation personalized, decentralized medical devices.
- The integration of 'onics' and 'omics' with 2D materials promises highly accurate and cost-effective POC solutions.
- Continued research in 2D material engineering will drive innovation in personalized healthcare.

