Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Measurements of Strain

Measurements of Strain

Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...

Normal Strain under Axial Loading

Normal Strain under Axial Loading

Normal strain under axial loading is an important concept in the field of mechanics of materials. Axial loading implies the application of a force along the axis of a material, like a column or bar. This force can either compress or stretch the material. In the context of axial loading, normal strain is the deformation experienced by the material in the direction of the loading force. It's calculated as the change in length divided by the original length of the material. This unitless ratio...

True Stress and True Strain

True Stress and True Strain

Engineering stress is calculated as the load divided by the original, undeformed cross-sectional area. It approximates a material under load. This approximation is especially relevant post-yield in ductile materials. Though engineering stress-strain diagrams are often used for their convenience and accessibility, they can sometimes fall short in accuracy, particularly when dealing with large strain values.
In contrast, true stress offers a more precise portrayal. It is computed by dividing the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Simplified and Refined Murine Model of Reversible Aortic Constriction for Characterizing Cardiac Functional Recovery.

JACC. Basic to translational science·2026

Same author

Molecular and cellular adaptations to extended hypothermic oxygenated perfusion in donation-after-circulatory-death hearts in a porcine model.

Frontiers in cardiovascular medicine·2026

Same author

A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section.

JOR spine·2026

Same author

Empagliflozin preserves cardiac function and modulates metabolism in a mouse model of Duchenne muscular dystrophy.

bioRxiv : the preprint server for biology·2026

Same author

Positive allosteric modulator of SERCA pump NDC-1171 attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy.

bioRxiv : the preprint server for biology·2026

Same author

MRA and Doppler ultrasound of laryngeal blood flow under hormonal and hydration modulation.

BMC research notes·2026

Same journal

Computational Determination of Effective Working Length in Experimental Torsion Testing of Long Bones.

Journal of biomechanical engineering·2026

Same journal

Hierarchical Experimental Characterization of the Human Rib Cage for Nonlethal Projectile Impact Applications.

Journal of biomechanical engineering·2026

Same journal

An in vitro Experimental Model for Investigating Aortic Pressure Dynamics Under Blunt Thoracic Impacts.

Journal of biomechanical engineering·2026

Same journal

Editorial.

Journal of biomechanical engineering·2026

Same journal

Student Paper Competition of the 2025 ASME SB3C Summer Bioengineering Conference.

Journal of biomechanical engineering·2026

Same journal

Biomechanical Principles of Temporal Muscle Activation in Functional Movements: Implications for Stability and Movement Coordination.

Journal of biomechanical engineering·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 5, 2025

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

Published on: May 8, 2012

Quantification of Internal Disc Strain Under Dynamic Loading Via High-Frequency Ultrasound.

Elnaz Ghajar-Rahimi¹, Diya D Sakhrani^1,2, Radhika S Kulkarni^1,2

¹Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907.

Journal of Biomechanical Engineering

|December 5, 2024

Summary

This summary is machine-generated.

High-frequency ultrasound quantifies intervertebral disc strain during dynamic loading. This novel method reveals heterogeneous strain patterns, crucial for understanding disc injury and developing computational models.

Keywords:

dynamic loading intervertebral disc strain texture correlation ultrasound

More Related Videos

An In Vitro Organ Culture Model of the Murine Intervertebral Disc

An In Vitro Organ Culture Model of the Murine Intervertebral Disc

Published on: April 11, 2017

A Novel Application of Musculoskeletal Ultrasound Imaging

A Novel Application of Musculoskeletal Ultrasound Imaging

Published on: September 17, 2013

Related Experiment Videos

Last Updated: Jun 5, 2025

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

Published on: May 8, 2012

An In Vitro Organ Culture Model of the Murine Intervertebral Disc

An In Vitro Organ Culture Model of the Murine Intervertebral Disc

Published on: April 11, 2017

A Novel Application of Musculoskeletal Ultrasound Imaging

A Novel Application of Musculoskeletal Ultrasound Imaging

Published on: September 17, 2013

Area of Science:

Biomechanics
Medical Imaging

Background:

Accurate measurement of intervertebral disc strain is vital for injury research and computational model validation.
Current noninvasive methods often use markers that affect tissue mechanics or are limited to static conditions.

Purpose of the Study:

To integrate high-frequency ultrasound and texture correlation for quantifying disc strain under dynamic loading.
To establish a noninvasive method for assessing internal disc mechanics during physiological conditions.

Main Methods:

Bovine intervertebral discs were imaged using high-frequency ultrasound in the transverse plane.
Axial compression (0-0.5 mm) at 0.3-0.5 Hz was applied dynamically.
Direct deformation estimation (DDE), a texture correlation technique, quantified internal Green-Lagrangian strains over time.

Main Results:

Median principal strains at maximal compression were 0.038±0.011 (E1) and -0.042±0.012 (E2).
Strain distribution was heterogeneous, with higher strains observed near the disc endplates.

Conclusions:

High-frequency ultrasound combined with texture correlation is a valuable tool for quantifying disc strain during dynamic loading.
This method has potential for clinical applications in diagnosing and managing disc diseases.