Myelin oligodendrocyte glycoprotein antibodyassociated disease (MOGAD): a pediatric case report
Dora S Gutiérrez1, María E Balbuena Aguirre2, Silvia D Castellano1
1Children's Intensive Care; Hospital de Clinicas José de San Martín, City of Buenos Aires, Argentina.
Abstract:
Recently, the disease associated with antibodies against the myelin glycoprotein of oligodendrocytes was described. It is characterized by clinical manifestations such as optic neuritis, transverse myelitis, and acute disseminated encephalomyelitis, among others. It occurs in children and young adults. Diagnosis is based on clinical findings and neurological imaging and is confirmed when antibodies against the myelin glycoprotein of oligodendrocytes are found in the blood. Given the pathology's severity, this study's result should not delay treatment. We present the case of a 15-year-old patient who was admitted with paresis of the upper limbs and paralysis of the lower limbs associated with acute urinary retention. During his hospitalization, the disease was suspected, and he was treated with good neurological evolution. Subsequently, the laboratory results confirmed the disease.
More Related Videos
08:03Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice
Published on: April 15, 2014
10:47Simple and Efficient Production and Purification of Mouse Myelin Oligodendrocyte Glycoprotein for Experimental Autoimmune Encephalomyelitis Studies
Published on: October 27, 2016
Related Concept Videos
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Viral Meningitis
Cytomegalovirus Disease
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Myasthenia Gravis ll: Pathophysiology
