Over-the-counter dermatology supplements- a practical guide to authenticity labels and reputable sources

Over-the-counter (OTC) oral supplements are increasingly used by consumers and recommended by dermatologists for managing various dermatologic conditions. Despite their popularity, these supplements often lack standardized regulation, potentially posing risks to both patients and clinicians. This review examines the importance of evaluating OTC oral supplements in dermatology, focusing on the prevalence and consequences of adulterated products and the implications of different authenticity labels for consumer education and clinical practice. Various authenticity labels are discussed, such as USP, NSF, ConsumerLab.com, and UL, which aim to verify supplement quality and safety. However, these labels have different criteria and methods for testing, leading to further confusion about their meanings and comparisons. This review provides practical guidance on evaluating OTC oral supplements and interpreting authenticity labels, aiming to help dermatologists and consumers make informed decisions and improve outcomes.