University student perspectives on antimicrobial peptide use in farm animals

Growing awareness of antimicrobial resistance (AMR) in livestock production has led to calls for the development of alternatives such as antimicrobial peptides (AMPs) that are also able to combat infectious diseases in farm animals. A critical step in the development of AMPs is to understand people's perspectives towards this technology to avoid misalignment with societal expectations. The aim of this study was to investigate university student perspectives of AMP applications in farm animals as alternatives to antibiotic use. We interviewed 20 university students and, using thematic analysis, identified six themes: 1) Initial knowledge, including knowledge of antibiotics and initial impressions of AMPs; 2) Human wellbeing, including the effects of food and animal health on public health, the importance of addressing AMR, and cost for farmers; 3) Animal welfare, including animal health, welfare, and production, and continuation of contentious farm practices; 4) Perceived naturalness of AMPs, including biocompatibility and comparing same and different species transfer of biological material; 5) Unforeseen consequences of AMPs, and the importance of researching unintended consequences of novel technologies; and 6) Public acceptance of AMPs, including trust and lack of awareness. In summary, participants viewed AMPs positively as an alternative to antibiotic use in farm animals to address AMR. However, key concerns centered around unintended harmful effects for food systems, public health, and animal welfare, which may impact public acceptance of AMPs in animal agriculture.