Related Experiment Video
Updated: Jun 24, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
Published on: December 9, 2016
A unique pediatric thoracic tumor: A case report of mediastinal Ewing sarcoma
Kamar Shaker1, Khaled Alomar2, Zaher Alabed1
1Damascus University, University pediatrics Hospital, Damascus, Syria.
Introduction And Significance:
Ewing's sarcoma is a rare tumor occurring in the mediastinum. It is a malignant, aggressive, and rapidly growing tumor that often lacks distinctive clinical or radiological features. Diagnosis is primarily made through histological and immunocytochemical examination. Complete surgical excision followed by chemotherapy is the preferred treatment.
Case Presentation:
We present a case of a child who initially presented with mild respiratory distress. The condition rapidly progressed, leading to an external misdiagnosis and the placement of a chest defibrillator due to misinterpreted findings. The child was referred to our institution, where a large mediastinal mass was diagnosed and surgical intervention was undertaken to completely resect the mass and confirm the diagnosis of Ewing's sarcoma.
Clinical Discussion:
It is crucial for medical practitioners, especially surgeons, to include Ewing's sarcoma in the differential diagnosis of mediastinal lesions. This consideration is essential for developing an appropriate surgical intervention plan and subsequent follow-up.
Conclusion:
Our case highlights several important points in clinical practice. It emphasizes the need to avoid relying solely on non-contrast CT scans when a mass is suspected. Additionally, fine-needle aspiration (FNA) should be considered for mass lesions to establish a diagnosis before surgical intervention, as some conditions, such as lymphoma, may not require surgery. Our case also demonstrates the successful removal of a large chest mass through a posterior lateral thoracic approach.
More Related Videos
04:04Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
07:50Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts
Published on: May 25, 2018
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...