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Updated: May 6, 2026

Terahertz Microfluidic Sensing Using a Parallel-plate Waveguide Sensor
Published on: August 30, 2012
Terahertz-based biosensors for biomedical applications: A review
Meraline Selvaraj1, Sreeja B S1, Mohamed Aly Saad Aly2
1Department of Electronics & Communication Engineering, College of Engineering Guindy, Anna University, Chennai 600025, India.
Terahertz (THz) biosensors offer a label-free, non-invasive method for detecting biomolecules. This review covers THz biosensor applications, sensitivity enhancements, and future prospects in biomedical fields.
Area of Science:
- Life Sciences
- Biomedical Engineering
- Spectroscopy
Background:
- Biosensors are crucial in healthcare, drug development, and environmental monitoring.
- Terahertz (THz) biosensing emerges as a promising label-free, non-invasive technique.
- THz Spectroscopy offers rapid, sensitive, and non-destructive biomolecule analysis.
Purpose of the Study:
- To review the significance and applications of THz-based biosensors.
- To summarize techniques for enhancing biosensor sensitivity and selectivity.
- To critically assess the challenges and future of THz biosensing.
Main Methods:
- Literature review of THz biosensor technology.
- Analysis of biomolecule detection and analysis using THz Spectroscopy.
- Comparative study of existing biosensor performance.
Main Results:
- THz biosensors demonstrate broad applicability in life sciences and healthcare.
- Various methods exist to improve THz biosensor sensitivity and selectivity.
- A performance comparison of different biosensors is presented.
Conclusions:
- THz biosensing holds significant potential for advanced biomedical applications.
- Continued research is needed to address challenges and unlock future prospects.
- This technology offers a powerful tool for label-free biomolecule detection.
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