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Related Experiment Video

Updated: Jun 5, 2025

An Improved Method for the Preparation of Type I Collagen From Skin

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Published on: January 21, 2014

Wessely-type immune ring following collagen cross-linking.

Mariana Domingues Vaz¹, Ines Machado², Tomás Loureiro²

¹Ophthalmology, Hospital Garcia de Orta EPE, Almada, Portugal marianadomvaz@gmail.com.

BMJ Case Reports

|December 5, 2024

Summary

Corneal collagen cross-linking for keratoconus can cause sterile infiltrates. Prompt steroid treatment and resumption are key for recovery, as seen in this case study.

Area of Science:

Ophthalmology
Corneal Surgery
Vision Science

Background:

Keratoconus is a progressive thinning of the cornea leading to visual impairment.

Keywords:

Eye Immunological products and vaccines

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Corneal collagen cross-linking (CXL) is a standard treatment to halt keratoconus progression.

Epithelial removal is a common step in some CXL protocols, potentially increasing infection or inflammation risk.