Related Experiment Video
Updated: Jun 5, 2025

05:17
An Improved Method for the Preparation of Type I Collagen From Skin
Published on: January 21, 2014
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Wessely-type immune ring following collagen cross-linking.
Mariana Domingues Vaz1, Ines Machado2, Tomás Loureiro2
1Ophthalmology, Hospital Garcia de Orta EPE, Almada, Portugal marianadomvaz@gmail.com.
BMJ Case Reports
|December 5, 2024
Summary
Corneal collagen cross-linking for keratoconus can cause sterile infiltrates. Prompt steroid treatment and resumption are key for recovery, as seen in this case study.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Vision Science
Background:
- Keratoconus is a progressive thinning of the cornea leading to visual impairment.
- Corneal collagen cross-linking (CXL) is a standard treatment to halt keratoconus progression.
- Epithelial removal is a common step in some CXL protocols, potentially increasing infection or inflammation risk.

