Harnessing artificial intelligence for enhanced veterinary diagnostics: A look to quality assurance, Part I Model...

Artificial intelligence (AI) has transformative potential in veterinary pathology in tasks ranging from cell enumeration and cancer detection to prognosis forecasting, virtual staining techniques, and individually tailored treatment plans. Preclinical testing and validation of AI systems (AIS) are critical to ensure diagnostic safety, efficacy, and dependability. In this two-part series, challenges such as the AI chasm (ie, the discrepancy between the AIS model performance in research settings and real-world applications) and ethical considerations (data privacy, algorithmic bias) are reviewed and underscore the importance of tailored quality assurance measures that address the nuances of AI in veterinary pathology. This review advocates for a multidisciplinary approach to AI development and implementation, focusing on image-based tasks, highlighting the necessity for collaboration across veterinarians, computer scientists, and ethicists to successfully navigate the complex landscape of using AI in veterinary medicine. It calls for a concerted effort to bridge the AI chasm by addressing technical, ethical, and regulatory challenges, facilitating AI integration into veterinary pathology. The future of veterinary pathology must balance harnessing AI's potential while intentionally mitigating its risks, ensuring the welfare of animals and the integrity of the veterinary profession are safeguarded. Part I of this review focuses on considerations for model development, and Part II focuses on external validation of AI.