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Updated: Jun 5, 2025

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Obsessive-Compulsive Disorder in Children and Adolescents: Early Detection in Primary Care Settings
Isheeta Zalpuri1, Morgan Matzke1, Shashank V Joshi1
1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA.
Abstract:
Obsessive-compulsive disorder (OCD) is a common and potentially debilitating condition affecting approximately 1%-3% of children and adolescents.1,2 It is characterized by obsessions and/or compulsions that are time-consuming or cause clinically significant distress or impairment in school, social, family, or other important areas of functioning. OCD can have a lasting impact on both academic and social functioning. For instance, engaging in rituals can lead to isolation, tardiness, family conflict, sleep alterations, and procrastination. Children with untreated OCD are also at elevated risk of developing substance use, episodes of depression, suicidal ideation and attempts.
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