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Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

46
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
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Related Experiment Video

Updated: Jun 5, 2025

Combination of High Ligation and Intraoperative Embolization using Polidocanol for Treatment of Varicoceles
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Initial experience with Double-vein Embolization in Hungary.

David Adam Korda1, Andras Bibok1, Attila Doros1

  • 1Semmelweis University, Department of Interventional Radiology, Határőr út 18, Budapest H-1122, Hungary.

European Journal of Radiology Open
|December 6, 2024
PubMed
Summary
This summary is machine-generated.

Double-vein Embolization safely induces liver hypertrophy before major surgeries, significantly increasing future liver remnant volume and function. This technique shows promise for improving outcomes in liver resection candidates.

Keywords:
Double-vein embolizationFuture liver remnantHepatic interventionHepatobiliary scintigraphyLiver regeneration

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Area of Science:

  • Hepatobiliary Surgery
  • Interventional Radiology
  • Surgical Oncology

Background:

  • Major hepatectomies require sufficient future liver remnant (FLR) volume and function.
  • Techniques to induce FLR hypertrophy are crucial for improving surgical outcomes.
  • Double-vein Embolization (DVE) is an emerging technique for FLR hypertrophy.

Purpose of the Study:

  • To summarize the initial experience with DVE at a Hungarian center.
  • To evaluate the safety and efficacy of DVE in inducing FLR hypertrophy.
  • To assess volumetric and functional changes in FLR after DVE.

Main Methods:

  • 16 DVE procedures were performed between March 2023 and August 2024.
  • FLR volume was assessed using CT scans pre- and post-procedure.
  • Hepatobiliary scintigraphy (Tc-99m mebrofenin) evaluated FLR function in 12 patients.

Main Results:

  • 100% technical success rate with no major complications.
  • Significant increase in FLR volume (433.1 to 603.5 cm³) and ratio (27.2% to 37%).
  • Significant improvement in FLR clearance and function, with mean function gain of 50.6% at 1 week and 60.1% at 2 weeks.

Conclusions:

  • DVE is a safe and effective procedure for inducing significant volumetric and functional FLR gain.
  • Outcomes are comparable to literature data, supporting DVE's role in liver resection.
  • Further studies are needed to establish DVE's definitive role in clinical practice.