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Prajesh K Bhunya1, Somdev Sil2, Amrita Sil1

  • 1Department of Pharmacology, Rampurhat Government Medical College, Hospital More, Birbhum, West Bengal, India.

Indian Dermatology Online Journal
|December 6, 2024
PubMed
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No abstract available in PubMed .

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Dipeptidyl peptidase 4 (DPP-4) is a serine protease widely distributed in the body. It's involved in the inactivation of GLP-1 and GIP hormones, which are crucial for insulin regulation. DPP-4 inhibitors, such as sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), alogliptin (Nesina), and vildagliptin (Galvus), help increase the proportion of active GLP-1, enhancing insulin secretion. These inhibitors work by competitively binding to DPP-4. This binding causes a...
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