Elucidating the dynamics of carbamazepine uptake using date pit-derived activated carbon: A comprehensive kinetic and
Ramez M Zayyat1, Rim Yahfoufi2, Mahmoud Al-Hindi2
1Department of Civil and Environmental Engineering, American University of Beirut, P.O. Box 11-0236, Riad El Solh, Beirut, 1107 2020, Lebanon.
Abstract:
Water contamination with pharmaceuticals such as Carbamazepine (CBZ) presents a significant environmental challenge. This study investigates the use of activated carbon derived from waste date pits (DPAC) for the removal of CBZ from water. The impact of several parameters such as pH, temperature, CBZ concentration, and flow rate on the adsorption were assessed. The generated DPAC demonstrated a specific surface area of 309 m2/g, a pore volume of 0.264 cm³/g, and the pores are mainly distributed at 1.86, 2.73, and 3.43 nm. The Langmuir, Freundlich, Sips, and Toth isotherms were used to fit the experimental data, and the results indicate the occurrence of monolayer adsorption and heterogeneous surface conditions. The Linear Driving Force model was used for kinetic analysis, showing improved fit at higher concentrations. Thermodynamic analyses revealed the process to be endothermic, spontaneous, and entropically driven. The DPAC achieved an adsorption capacity of 14.89 mg/g and maintained 94 % effectiveness after the first regeneration cycle and 70 % after four cycles. This study highlights the potential of DPAC as a sustainable adsorbent for advanced water purification.
More Related Videos
Related Concept Videos
Determination of Michaelis Constant and Maximum Elimination Rate
These parameters can be estimated by analyzing plasma concentration data post-drug administration. A notable example of this application is phenytoin, a drug with capacity-limited kinetics. It's recommended that phenytoin should be administered at two...
Nonlinear Pharmacokinetics: Michaelis-Menten Equation
Vmax represents the maximum achievable process rate, while KM, known as the Michaelis constant, signifies the drug concentration at which the process rate reaches half its maximum. This relationship between Vmax, KM, and Cp gives rise to three distinct...
One-Compartment Open Model for IV Bolus Administration: Estimation of Elimination Rate Constant, Half-Life and Volume of Distribution
Drug Distribution as One-Compartment Model and Elimination by Nonlinear Pharmacokinetics: Overview
For instance, consider the metabolism of sodium salicylate. This compound is metabolized into two distinct substances: a glucuronide and a glycine conjugate. The rate of conjugation depends...
Two-Compartment Open Model: IV Bolus Administration
The disparity between drug input and the sum of drug transfer rates between...
Fundamental Mathematical Principles in Pharmacokinetics: Calculus and Graphs
On the other hand, integral calculus focuses on...

![Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59557.jpg&w=3840&q=50)
