Related Experiment Video
Updated: Jun 5, 2025

05:10
Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice
Published on: October 3, 2010
12.2K
A rare case of granular cell tumor affecting the upper back in a child
1Department of pediatric surgery, Indira Gandhi Institute of Child Health, Bengaluru, India.
Rare Tumors
|December 6, 2024
Abstract:
Granular cell tumors (GCT) are rare mesenchymal tumors belonging to Schwann cell lineage constituting 0.5% of all soft tissue neoplasms. They occur in skin, subcutaneous tissues, mucosal surfaces including within the deeper organs. They are considered unusual and unique neoplasm due to their distinctive pathologic diagnosis. Such a rare case has been discussed here due to unusual age at presentation and in its location.
Related Concept Videos
The Retinoblastoma Gene
4.1K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.1K
Tumor Progression
6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K

