Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reversal of Soleus Muscle Atrophy in Older Adults: A Non-Volitional Exercise Intervention for a Changing Climate.

Clinical interventions in aging·2024
Same author

Pulsed shortwave electromagnetic field therapy increases quality of life in canines with symptoms of osteoarthritics.

Veterinary medicine and science·2024
Same author

Reversal of cognitive impairment in a hypotensive elderly population using a passive exercise intervention.

Clinical interventions in aging·2017
Same author

Postural Hypotension and Cognitive Function in Older Adults.

Gerontology & geriatric medicine·2017
Same author

Association of Calf Muscle Pump Stimulation With Sleep Quality in Adults.

Research in nursing & health·2016
Same author

Calf muscle pump stimulation as a means to reduce symptoms of fibromyalgia syndrome.

Biological research for nursing·2014

Related Experiment Video

Updated: Jun 5, 2025

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
07:53

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

Published on: September 13, 2015

21.8K

Characterizing Soleus Muscle Response to Targeted Plantar Nerve Modulation Using Mechanomyography.

Kenneth J McLeod1

  • 1Sonostics, Inc, Endicott, NY, USA.

Neuromodulation : Journal of the International Neuromodulation Society
|December 6, 2024
PubMed
Summary
This summary is machine-generated.

Plantar nerve stimulation enhances soleus muscle activity in older adults, reversing age-related atrophy. This noninvasive therapy rejuvenates muscles, improving health and supporting cardiac output during upright posture.

Keywords:
Mechanomyographyplantar nerve modulationsoleus muscle atrophy

More Related Videos

Measuring Neuromuscular Junction Functionality
10:40

Measuring Neuromuscular Junction Functionality

Published on: August 6, 2017

17.9K
Non-invasive Assessment of Changes in Corticomotoneuronal Transmission in Humans
09:30

Non-invasive Assessment of Changes in Corticomotoneuronal Transmission in Humans

Published on: May 24, 2017

7.8K

Related Experiment Videos

Last Updated: Jun 5, 2025

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
07:53

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation

Published on: September 13, 2015

21.8K
Measuring Neuromuscular Junction Functionality
10:40

Measuring Neuromuscular Junction Functionality

Published on: August 6, 2017

17.9K
Non-invasive Assessment of Changes in Corticomotoneuronal Transmission in Humans
09:30

Non-invasive Assessment of Changes in Corticomotoneuronal Transmission in Humans

Published on: May 24, 2017

7.8K

Area of Science:

  • Physiology
  • Gerontology
  • Biomedical Engineering

Background:

  • The soleus muscle is crucial for maintaining cardiac output during upright posture.
  • Age and disuse cause soleus atrophy, leading to health issues in older adults.
  • Exogenous stimulation technology offers potential for soleus muscle rejuvenation.

Purpose of the Study:

  • To investigate the influence of plantar nerve stimulation on soleus muscle activity.
  • To optimize stimulation technology for soleus muscle rejuvenation in older adults.

Main Methods:

  • Mechanomyographic (MMG) spectra were used to characterize soleus muscle dynamics in adults during quiet sitting.
  • Soleus spectra from older women (with and without plantar nerve modulation) were compared to those of young adults.
  • Plantar nerve modulation was applied to assess its immediate and sustained effects.

Main Results:

  • Young men exhibit high tonic soleus activity involving type I and IIa fibers.
  • Young women show lower frequency type I and reduced type IIa activity compared to men.
  • Older women display reduced type I activity, indicative of disuse atrophy.
  • Plantar nerve modulation significantly enhanced soleus activity across the type I fiber spectrum (p < 0.0001).
  • Sustained daily modulation in older women improved fiber dynamics, resembling those of young women.

Conclusions:

  • MMG analysis confirms plantar nerve modulation enhances soleus muscle performance short- and long-term.
  • Noninvasive nerve modulation therapy can rejuvenate soleus muscles, counteracting detrimental health conditions in older adults.
  • MMG is valuable for optimizing nerve modulation strategies for soleus muscle applications.