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Eculizumab Improves Renal Survival in Complement-Mediated TMA Secondary to SLE

Yakai Fu1, Zhiwei Chen1, Jie Chen1

  • 1Department of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Mayo Clinic Proceedings
|December 6, 2024
PubMed
Abstract

No abstract available in PubMed .

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Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
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