Alveolar Bone Tissue Engineering Using Deciduous Dental Pulp Stem Cells in a Patient with Cleft Lip and Palate

The use of tissue bioengineering strategies in dentistry has gained relevance. Many studies indicate that stem cells associated with biomaterials can regenerate intraoral tissues and have been applied to patients with cleft lip and palate (CLP). One of the treatments is alveolar bone reconstruction through bone grafts, where the bone is removed from the donor site and placed in the alveolar cleft. The use of stem cells from deciduous dental pulp, associated with a hydroxyapatite and collagen scaffold, can eliminate the need for autologous bone grafts, reducing pain and morbidity at the donor site. This study presents a case report in which a patient with cleft lip and palate was treated using this technique, resulting in complete filling of the alveolar cleft after 12 months.