Related Experiment Video
Updated: Jun 5, 2025

NMR Spectroscopy as a Robust Tool for the Rapid Evaluation of the Lipid Profile of Fish Oil Supplements
Published on: May 1, 2017
Feasibility of Fish Oil Supplementation on Headache Symptoms and Blood Lipids in Migraine Patients
En-Ling Yeh1, Chun-Pai Yang1,2, Shu-Wen Lin3
1Department of Nutrition, Hungkuang University, Taichung, Taiwan.
Objectives:
Migraine is a chronic, recurring, and disabling disease. Fish oil intervention was used to investigate its effects on headache symptoms and blood lipids of migraine patients.
Design:
All subjects were collected at the Kuang Tian General Hospital from March 2020 to May 2021. Experimental group subjects took 1 g/time of fish oil (including EPA 900 mg/tablet) after breakfast and dinner. Placebo group subjects took 100% soybean oil twice daily. Before and after the test, the migraine improvement questionnaire was used to analyze headaches during attacks, dietary intake, and headache triggers.
Results:
The average age of the 47 subjects in this study was 40.3 ± 9.2 years old, the body mass index (BMI) was 24.3 ± 6.0 kg/m2. At Week 12, subjects in the fish oil group were significantly improved relative to the control group (p < 0.05). Blood lipid indexes TC, LDL-C, and TG were reduced, and the frequency, duration, and pain degree of migraine.
Conclusion:
Fish oil may be used as an adjunctive therapeutic food for relieving migraine attack symptoms and blood lipids.

