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Updated: Jun 5, 2025
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Pregnancy outcomes in adolescent and young adult patients with multiple sclerosis: A case series
Gina Chang1, Sarah Stoney1, Sona Narula1,2
1Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Background:
While there is increasing understanding of the effect of pregnancy on the clinical course of multiple sclerosis (MS), there are limited studies focused on younger populations.
Cases:
We report neurologic and obstetric outcomes for 14 pregnancies from 11 adolescent and young adult female patients with pediatric-onset MS who delivered live births prior to age 26, and describe their relevant social determinants of health.
Conclusion:
Neurologic and obstetric outcomes in this cohort were generally good. Many of the pregnancies in our cohort appeared unplanned, underscoring the importance of discussing family planning with all MS patients of childbearing potential.
