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Toxin for Tics: Practical Guidance for Clinicians from a Registry-Based Naturalistic Study
Tamara Pringsheim1, Davide Martino1
1Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Movement Disorders Clinical Practice
|December 7, 2024
Summary
Botulinum toxin injections are a well-tolerated and effective treatment for adults with tics. This study provides practical guidance on using botulinum toxin for tic disorders, detailing muscles injected and dosages.
Area of Science:
- Neurology
- Pharmacology
Background:
- Botulinum toxin is a recommended treatment for tics.
- Limited practical guidance exists for its clinical application.
Purpose of the Study:
- To describe the clinical experience with botulinum toxin injections for adult tics.
- To provide practical guidance on tics treated, muscles injected, and dosages.
Main Methods:
- Analysis of data from the Calgary Adult Tic Registry.
- Assessment of tic severity, muscles injected, dosages, treatment duration, and concurrent medications.
Main Results:
- Botulinum toxin was used by 33.7% of participants.
- Commonly treated motor tics included blinking, head turns, and shoulder raising.
- Mean treatment duration was 40.4 months.
Conclusions:
- Botulinum toxin is an effective and well-tolerated treatment for adult tics.
- The findings offer practical insights for clinicians.
