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Novel Perspective on Sevoflurane-Induced Cognitive Dysfunction: Implications of Neuronal SIRPα and Microglial

Wei Du1, Xiaomin Zhang1, Songze Li1

  • 1Department of Anesthesiology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang 110042, China.

ACS Chemical Neuroscience
|December 7, 2024
PubMed

Keywords:
microglial cellsneuronssevofluranesignal-regulatory protein αsocial cognitive impairmentssynaptic remodeling

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Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
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