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[Evaluation of intracranial calcification associated with aging by computerized tomography]
No to Shinkei = Brain and Nerve
|February 1, 1986
Summary
Intracranial calcification, including the pineal region, choroid plexus, and falx cerebri, increases with age. Cerebral arterial calcification may decrease in very long-lived individuals.
Area of Science:
- Neurology
- Radiology
- Gerontology
Background:
- Intracranial calcification is a common finding in neuroimaging.
- Its relationship with the aging process requires further investigation.
Purpose of the Study:
- To investigate the association between intracranial calcification and aging.
- To analyze the prevalence of calcification in different intracranial structures across age groups.
Main Methods:
- Retrospective analysis of 450 normal computerized tomography (CT) scans.
- Subjects categorized into nine age groups.
- Evaluation of calcification in the pineal region, choroid plexus, falx cerebri, and cerebral arteries.
Main Results:
- Pineal region calcification observed in ~70% of individuals over 30.
- Choroid plexus and falx cerebri calcification increased with age.
- Cerebral arterial calcification prevalent in older groups, with a potential decrease in the ninth decade.
Conclusions:
- Intracranial calcification, particularly in the choroid plexus and falx cerebri, is strongly associated with aging.
- Cerebral arterial calcification patterns may suggest a protective factor in longer-lived individuals.