Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

690
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
690
Pharmacovigilance01:19

Pharmacovigilance

773
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
773
Drug Concentrations: Measurements01:23

Drug Concentrations: Measurements

326
Drug concentration is the quantity of a drug present in a biological sample. Measuring drug amounts in biological samples allows the clinician to understand how a drug is absorbed, distributed, metabolized, and excreted. Samples can be obtained through invasive or non-invasive methods. Invasive techniques involve surgical or parenteral interventions to gather blood, cerebrospinal fluid, or tissue biopsy. Conversely, non-invasive approaches provide samples like urine, feces, and saliva.
Plasma...
326
Drug Regulation01:25

Drug Regulation

1.3K
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
1.3K
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

232
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
232
Drug Classes and Categories01:25

Drug Classes and Categories

1.9K
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analytical Methods for the Quantification of Drugs and Their Metabolites in Human Hair: A Systematic Review From 2010 to 2025.

Drug testing and analysis·2026
Same author

Unsolicited Email and Predatory Solicitations: A Retrospective Case Study of a Canadian Hospital Pharmacist and the Tip of a Larger Iceberg.

The Canadian journal of hospital pharmacy·2026
Same author

[Observatory of scientific publications by Quebec pharmacists: An exploratory survey].

Annales pharmaceutiques francaises·2026
Same author

Novel Genetic Risk Factor Identified for L-Asparaginase-Induced Pancreatitis in Pediatric Patients With Cancer.

Pediatric blood & cancer·2026
Same author

[Profile of training courses offered in clinical pharmacy in hospitals: An exploratory North-South study].

Annales pharmaceutiques francaises·2026
Same author

Survey of Guidance for Authors on the Use of Generative Artificial Intelligence in Pharmaceutical Journals.

The Canadian journal of hospital pharmacy·2026

Related Experiment Video

Updated: Jun 5, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

9.6K

Drug shortages in Canada, 2019-2023: A descriptive study.

Ilona Béatrix1, Elsa Bonnabry1, Suzanne Atkinson1

  • 1CHU Sainte-Justine, 3175, chemin de la Côte Sainte-Catherine, Montréal, Québec H3T 1C5, Canada.

Annales Pharmaceutiques Francaises
|December 7, 2024
PubMed
Summary

Canada experienced a high volume of drug shortages from 2019-2023, impacting both the general and hospital markets. While episode duration decreased, the number of manufacturers involved rose, highlighting an ongoing challenge.

Keywords:
CanadaDrugsGrossisteHospitalHôpitalMédicamentsPénurieShortagesWholesaler

More Related Videos

A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats
10:35

A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats

Published on: November 11, 2013

11.1K
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

12.8K

Related Experiment Videos

Last Updated: Jun 5, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

9.6K
A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats
10:35

A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats

Published on: November 11, 2013

11.1K
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

12.8K

Area of Science:

  • Pharmaceutical Sciences
  • Health Services Research
  • Public Health

Background:

  • Global drug shortages are a growing concern, with European countries reporting increased issues in 2023.
  • Understanding national drug shortage trends is crucial for patient care and healthcare system stability.

Purpose of the Study:

  • To comprehensively analyze drug shortage episodes in Canada between September 2019 and December 2023.
  • To identify patterns and characteristics of drug shortages within the Canadian healthcare landscape.

Main Methods:

  • Utilized two primary data sources: the Canadian mandatory drug shortage reporting website and hospital wholesaler data.
  • Conducted descriptive statistical analyses on a 52-month dataset spanning from September 1, 2019, to December 31, 2023.
  • Examined both community and hospital settings for drug shortage reporting.

Main Results:

  • Reported 10,975 shortage episodes and 1,087 discontinuations via the Canadian website, alongside 2,562 episodes from hospital wholesaler data.
  • Median episode duration was 51 days (website data) versus 145 days (wholesaler data).
  • Data involved 184 manufacturers (website) and 83 manufacturers (wholesaler); only 86 episodes were Tier 3.

Conclusions:

  • The study confirms a significant number of drug shortages in Canada, affecting both the overall market and hospital settings.
  • Despite a decrease in median episode duration, an increase in the number of involved manufacturers signals a complex and evolving challenge.
  • There is a critical need to avoid normalizing or accepting the current drug shortage situation as inevitable.