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The mediating role of processing speed on the relationship between executive functions and social cognition in
Triantafyllos Doskas1,2, Constantinos Kormas3, Liberis Dekavallas1
1Department of Neurology, Athens Naval Hospital, Athens, Greece.
Abstract:
This study examined the mediating role of processing speed between executive functions and social cognition in 67 relapsing-remitting multiple sclerosis (RRMS) patients. Executive functions were assessed using the Trail Making Test-Part B (TMT-B) and the Stroop Neuropsychological Screening Test (SNST); social cognition with the Reading the Mind in the Eyes Test (RMET); and processing speed with the Symbol Digit Modalities Test (SDMT). Mediated effects were explored using a series of regression analyses and were further confirmed through bootstrapping procedures. Results revealed that processing speed partially mediated the relationship between cognitive shifting (TMT-B) and social cognition (RMET), and fully mediated the relationship between inhibitory control (SNST) and social cognition (RMET). These findings highlight the importance of processing speed in the socio-cognitive impairments observed in RRMS patients, thus suggesting that comprehensive assessments and targeted interventions in this clinical group.
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