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Localised apolipoprotein A-I amyloidosis arising in a fibroadnexal hamartoma in a dog
Tomoaki Murakami1, Kenta Owaku1, Natsumi Kobayashi1
1Laboratory of Veterinary Toxicology, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan.
Veterinary Dermatology
|December 9, 2024
Abstract:
Canine apolipoprotein A-I (ApoA-I) amyloidosis has only been reported as an age-related pulmonary vascular condition. In this report, the authors identified cutaneous ApoA-I amyloidosis within a fibroadnexal hamartoma in a dog. Based on proteomic analysis using mass spectrometry, the mechanism of ApoA-I amyloidogenesis is discussed.
