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Primary hepatic leiomyosarcoma masquerading as liver abscess: A case report.
Fang-Nan Wu1, Min Zhang2, Kun Zhang1
1Department of Hepatobiliary and Pancreatic Surgery, Lishui Municipal Central Hospital, Lishui 323000, Zhejiang Province, China.
World Journal of Gastrointestinal Surgery
|December 9, 2024
Summary
Primary hepatic leiomyosarcoma (PHL) is a rare liver cancer. This case highlights PHL mimicking a liver abscess, emphasizing the need for careful diagnosis of hepatic lesions.
Area of Science:
- Hepatology
- Oncology
- Radiology
Background:
- Primary hepatic leiomyosarcoma (PHL) is a rare liver malignancy.
- PHL often presents with non-specific symptoms and imaging findings, complicating diagnosis.
- Distinguishing PHL from other hepatic lesions like liver abscesses preoperatively is challenging.
Observation:
- A 34-year-old woman presented with fever and right upper quadrant pain.
- Initial imaging revealed a thick-walled hepatic lesion with low-density areas, suggestive of a liver abscess.
- Percutaneous liver biopsy and subsequent hepatectomy were performed.
Findings:
- Postoperative pathology confirmed the diagnosis of primary hepatic leiomyosarcoma (PHL).
- The patient received intravenous chemotherapy with the AD regimen.
- The patient is currently disease-free with no signs of recurrence.
Implications:
- PHL should be considered in the differential diagnosis of hepatic lesions with specific imaging features.
- Key imaging indicators for considering PHL include a thick-walled hepatic lesion with a rich blood supply and significant uneven low-density areas.
- Early and accurate diagnosis is crucial for effective treatment and improved patient outcomes in rare liver tumors.

