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Updated: Jun 5, 2025

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Endogenous Endophthalmitis in the Setting of Kidney Disease: A Case Series
Ramakrishnan Santanaraman1, Ramprasad Ramalingam1, Dilip Rangarajan1
1Department of Nephrology, NU Hospitals, Bangalore, India.
Abstract:
Blood stream infections (BSI) are common in patients with kidney disease. Metastatic foci of infections are one of the known complications of BSI. Endophthalmitis which is defined as infection and inflammation of the inner coats of the eye ball and intraocular fluids (aqueous and vitreous), is one such focus. We discuss the clinical profile of five patients who had endogenous endophthalmitis in the setting of kidney disease and their management and outcome. All five had diabetes mellitus; the source was central venous catheter in two and urinary tract infection in two. Microbial cause was Staphylococcus aureus in two, Pseudomonas aeruginosa in one, Klebsiella pneumoniae in one and Candida albicans in one. All five required dialysis. Recovery of vision was poor with partial recovery only in two patients. A vision-threatening emergency, this condition requires early identification and management for better recovery of vision.

