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Neurorestorative therapeutic strategies for sequela of central nervous system infections

Hongyun Huang1, Paul R Sanberg2, Hari Shanker Sharma3

  • 1Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China.

Infectious Medicine
|December 9, 2024
PubMed
Abstract

No abstract available in PubMed .

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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