Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Astrocytomas in childhood: a population-based study.

G J Dohrmann, J R Farwell, J T Flannery

    Surgical Neurology
    |January 1, 1985
    PubMed
    Summary

    This population-based study analyzed pediatric astrocytomas over 42 years. Cerebellar astrocytomas showed the best survival rates, while brainstem tumors had the shortest survival in children.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The microvasculature in transitory traumatic paraplegia. An electron microscopic study in the monkey.

    Journal of neurosurgery·2011
    Same author

    Histopathology of transitory traumatic paraplegia in the monkey.

    Journal of neurosurgery·2011
    Same author

    History of intraoperative ultrasound in neurosurgery.

    Neurosurgery clinics of North America·2001
    Same author

    Late cognitive effects of early treatment with phenobarbital.

    Clinical pediatrics·1999
    Same author

    Major neurosurgical discoveries in the last 20 years.

    Surgical neurology·1999
    Same author

    Cigarette smoking and changes in the histopathology of lung cancer.

    Journal of the National Cancer Institute·1997

    Area of Science:

    • Pediatric Oncology
    • Neuro-oncology
    • Epidemiology

    Background:

    • Astrocytomas are common pediatric brain tumors.
    • Population-based studies reduce bias in epidemiological research.
    • Understanding incidence and survival is crucial for pediatric neuro-oncology.

    Purpose of the Study:

    • To report on the incidence and survival of childhood astrocytomas.
    • To analyze survival rates based on tumor location.
    • To identify trends in pediatric astrocytoma diagnosis.

    Main Methods:

    • Population-based study design over a 42-year period.
    • Inclusion of 179 diagnosed cases of pediatric astrocytoma.
    • Analysis of survival probabilities by tumor location and time.

    Main Results:

    • Over half of astrocytomas were located in the cerebellum.
    • A diagnostic peak occurred between 1965 and 1970.
    • Survival probabilities at 5 years was 0.667, decreasing to 0.538 at 20 years.
    • Cerebellar astrocytomas had the longest survival, brainstem tumors the shortest.

    Conclusions:

    • Tumor location significantly impacts survival in pediatric astrocytoma.
    • Cerebellar astrocytomas offer a better prognosis compared to other locations.
    • Long-term survival for childhood astrocytomas remains a significant challenge.

    Related Experiment Videos