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Changes in the frequency, presentation and surgical outcomes of complicated appendicitis during the pandemic
Tunc Eren1, Leyla Zeynep Tigrel1, Abdullah Kayali1
1Department of General Surgery, Istanbul Medeniyet University Faculty of Medicine, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye.
Insights
The COVID-19 pandemic saw fewer appendectomies but a significant rise in complicated appendicitis cases and postoperative complications. This highlights increased risks for patients during the pandemic.
Area of Science:
- Surgery
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic profoundly impacted global healthcare systems and patient care.
- Acute appendicitis remains a common surgical emergency requiring timely intervention.
Purpose of the Study:
- To evaluate the influence of the COVID-19 pandemic on the frequency, presentation, and surgical outcomes of complicated appendicitis.
- To compare appendicitis cases and outcomes in the pre-pandemic and pandemic periods.
Main Methods:
- A retrospective analysis of 409 patients who underwent appendectomy.
- Comparison of appendicitis cases one year before and one year after the pandemic declaration.
- Statistical analysis of demographics, diagnostic findings, and surgical outcomes.
Main Results:
- A decrease in weekly appendectomies during the pandemic (median 3 vs. 5).
- Increased time to hospitalization, elevated C-reactive protein levels, and higher postoperative complication rates during the pandemic.
- A 2.1-fold increased risk of complicated appendicitis during the pandemic (15.5% vs. 7.9%).
Conclusions:
- Fewer appendectomies were performed during the COVID-19 pandemic.
- The incidence of complicated appendicitis and associated postoperative complications significantly increased during the pandemic.
Objective:
Coronavirus Disease 2019 (COVID-19) has affected every aspect of human life and all health care systems globally. The aim of this study was to investigate the effect of COVID-19 pandemic on the frequency, presentation and surgical outcomes of complicated appendicitis.
Methods:
Patients who underwent appendectomy for acute appendicitis one year before and one year after the declaration of the pandemic were investigated. Demographics and diagnostic findings as well as surgical and histopathological outcomes were recorded and statistically analyzed.
Results:
The study group of 409 patients was composed of 241 cases in the pre-pandemic group and 168 cases in the pandemic group revealing that the weekly total number of appendectomies decreased during the pandemic [pre-pandemic, median (IQR): 5 (3-6); pandemic, median (IQR): 3 (2-5); p=0.005]. The pandemic group was significantly associated with a longer time from emergency department admission to hospitalization, increased mean blood C-reactive protein levels and increased rate of postoperative complications (p=0.024, p=0.038 and p=0.004, respectively). Most importantly, pathological examinations revealed a higher number of complicated appendicitis cases in the pandemic group when compared to the pre-pandemic group [26 (15.5%) vs. 19 (7.9%), respectively] which corresponded to a 2.1-fold higher risk of being diagnosed with complicated appendicitis during the pandemic [OR: 2.1 (95% CI: 1.1-4.1), p=0.024].
Conclusion:
While fewer appendectomies were performed during the pandemic, the incidence of complicated appendicitis and postoperative complications increased considerably.
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