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Updated: Jun 5, 2025

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
Published on: July 5, 2017
An innovative technique for the extraction and stability of polyphenols using high voltage electrical discharge:
Leila Abbaspour1, Nazila Ghareaghajlou1, Mohammad Reza Afshar Mogaddam2
1Students Research Committee, Department of Food Science and Technology, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract:
Polyphenols are the main group of phytochemicals with several biological activities. Due to the adverse effects of conventional solvent extraction methods, innovative extraction techniques have been used as alternatives to overcome these problems. High voltage electric discharge (HVED) is an eco-friendly innovative extraction technique based on the phenomenon of electrical breakdown in water. This technique induces physical and chemical processes, leading to product fragmentation, cellular damage, and liberation of bioactive compounds. HVED treatment can extract polyphenols at lower temperatures and shorter times than the conventional solvent extraction methods. This review summarizes the effect of HVED processing parameters on the recovery and stability of polyphenols from plant sources. Hydroethanolic solutions improve the HVED-assisted extraction of polyphenols compared to water. Moreover, acidic solvents are suitable for the high recovery and protection of polyphenols during electric discharges. This study revealed the efficacy of the HVED technique in extracting polyphenols for their utilization in the food and pharmaceutical industries.
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