Related Experiment Video
Updated: Aug 17, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Outcomes of pediatric sterile keratitis posthypotonic collagen cross-linking
Amanjot Kaur1, Srikant Kumar Sahu2, Prashant Garg3
1Cornea and Anterior Segment, Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Vijayawada, Andhra Pradesh, India.
Insights
Sterile keratitis can occur post-hypotonic collagen cross-linking (CXL) in children. Prompt treatment with steroids and lubricants led to complete resolution with minimal scarring and visual recovery.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Pediatric Eye Care
Background:
- Hypotonic collagen cross-linking (CXL) is a treatment for corneal conditions.
- Complications such as sterile keratitis can arise post-procedure.
- Understanding pediatric CXL outcomes is crucial.
Abstract:
In this case series, we will describe sterile keratitis in the early postoperative period after hypotonic collagen cross-linking (CXL) in two pediatric cases. This is a retrospective case series of two eyes of two children who developed inflammatory keratitis with central corneal haze after uneventful epithelial-off hypotonic CXL. After ensuring microbiological sterility, appropriate treatment with topical steroids and lubricants was started. There was complete resolution of corneal infiltrates with minimal scarring. Both patients regained almost the preoperative best-corrected visual acuity of 20/80 and 20/60, respectively.
Related Concept Videos
Development of Human Microbiota
The Skin Microbiota
Microbiome of the Eye
Development of the Oral Microbiota
Microbiota Modulation by Antibiotics
Acne Infection

