Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcriptomic Subgroups in Soft Tissue Tumors Correlate with Morphologic Subtype, Genomic Features, and Outcome.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026
Same author

Fine-Needle Aspiration of Parotid Gland Sialoblastoma. Two New Cases and Literature Review.

Diagnostic cytopathology·2025
Same author

MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma.

Communications biology·2024
Same author

Cytology of a parietal swelling in a 52-year-old man.

Cytopathology : official journal of the British Society for Clinical Cytology·2023
Same author

Pitfalls in soft tissue cytopathology.

Cytopathology : official journal of the British Society for Clinical Cytology·2023
Same author

The Influence of Surgeon Sex on Adverse Events Following Primary Total Hip Arthroplasty: A Register-Based Study of 11,993 Procedures and 200 Surgeons in Swedish Public Hospitals.

The Journal of bone and joint surgery. American volume·2022

Related Experiment Video

Updated: Jun 5, 2025

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

2.7K

Reporting Bone Cytopathology-A Proposal Based on a Single Tertiary Centre Experience.

Jan Köster1,2, Camila Bedeschi Rego De Mattos3, Henryk A Domanski2,4

  • 1Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden.

Cytopathology : Official Journal of the British Society for Clinical Cytology
|December 9, 2024
PubMed
Summary

Fine-needle aspiration cytology (FNAC) of bone lesions is a sensitive and specific tool. This study evaluated its diagnostic utility and proposed a standardized reporting system for bone cytopathology, showing high accuracy across tumor types.

Keywords:
bone tumourscytologycytopathologyfine‐needle aspirationreporting system

More Related Videos

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
12:04

Assessment of Bone Fracture Healing Using Micro-Computed Tomography

Published on: December 9, 2022

1.8K
Author Spotlight: Exploring Advanced Therapeutic Targets in Osteosarcoma Through Spatial Transcriptomics
07:43

Author Spotlight: Exploring Advanced Therapeutic Targets in Osteosarcoma Through Spatial Transcriptomics

Published on: May 3, 2024

2.5K

Related Experiment Videos

Last Updated: Jun 5, 2025

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

2.7K
Assessment of Bone Fracture Healing Using Micro-Computed Tomography
12:04

Assessment of Bone Fracture Healing Using Micro-Computed Tomography

Published on: December 9, 2022

1.8K
Author Spotlight: Exploring Advanced Therapeutic Targets in Osteosarcoma Through Spatial Transcriptomics
07:43

Author Spotlight: Exploring Advanced Therapeutic Targets in Osteosarcoma Through Spatial Transcriptomics

Published on: May 3, 2024

2.5K

Area of Science:

  • Cytopathology
  • Bone pathology
  • Oncology

Background:

  • Fine-needle aspiration cytology (FNAC) is valuable for bone lesions but lacks standardization.
  • Developing a standardized reporting system is crucial for consistent diagnosis.

Purpose of the Study:

  • Evaluate the diagnostic utility of FNAC for bone lesions.
  • Propose and test a standardized reporting system for bone cytopathology.

Main Methods:

  • Retrospective analysis of 721 bone lesion FNAC cases (2015-2023).
  • Assessed diagnostic performance using sensitivity, specificity, and accuracy.
  • Categorized diagnoses and calculated the risk of malignancy (ROM).

Main Results:

  • FNAC demonstrated 89% sensitivity and 99% specificity in differentiating benign and malignant lesions.
  • Overall diagnostic accuracy was 65%, varying by lesion type.
  • Risk of malignancy ranged from 6.7% (Benign) to 100% (Malignant).

Conclusions:

  • FNAC of bone lesions is a highly sensitive and specific diagnostic method.
  • The study offers insights for a standardized bone cytopathology reporting system.
  • Standardization can improve diagnostic accuracy and patient management.