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Updated: Jun 5, 2025

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
Using environmental and exercise physiology to address gender inequalities in climate change and occupational health
1School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK.
Abstract:
Climate change is a health-risk and health-inequity multiplier with excessive heat exposure a direct climate change impact already affecting the health and livelihood of billions globally. Women face greater risks and burdens from climate change impacts. Biological sex may or may not influence an individual's thermoregulatory capacity, heat tolerance or heat susceptibility. However at a population level, sex differences in physiological characteristics (anthropometrics, aerobic capacity, etc.) likely affect thermoregulatory capacity. Still, gender appears to play the most significant role in heat exposure and resulting health impacts. For climate change resilience and adaptation strategies to be effective, public health and occupational guidance/governance must be based on comprehensive and representative evidence. The current dearth of empirical evidence on how excessive heat exposure affects women prohibits this. Environmental and exercise physiology can help address this lack of empirical evidence by adhering to inclusive research guidelines. This paper is based on a symposium presentation given at Physiology 2023 in Harrogate, UK. Using a multi-year cohort study on industrial agricultural workers (the Adelante Initiative) as a case study, this review discusses the role of environmental and exercise physiology in generating inclusive research and evidence to inform occupational and public health guidance/governance for climate change resilience and adaptation, specifically heat exposure.
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