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An Atypical Mpox Presentation With a Large, Chronic Right Upper Eyelid Ulcerative Mass
Elise E Steinberger1, Dakota St Pierre2, Thai Do1
1Department of Ophthalmic Plastic and Reconstructive Surgery, Dean A. McGee Eye Institute.
Ophthalmic Plastic and Reconstructive Surgery
|December 9, 2024
Summary
Mpox can cause severe eye complications. This case highlights atypical eyelid lesions in an HIV-positive patient, emphasizing prompt Mpox diagnosis and treatment to prevent delayed care.
Area of Science:
- Infectious Diseases
- Ophthalmology
- Dermatology
Background:
- The global Mpox outbreak presents challenges, including potential ophthalmologic complications.
- Atypical presentations can complicate diagnosis, especially in immunocompromised individuals.
Purpose of the Study:
- To report a case of atypical Mpox infection presenting as a persistent eyelid lesion in an HIV-positive patient.
- To emphasize the importance of considering Mpox in the differential diagnosis of unusual periorbital lesions.
Main Methods:
- Retrospective case report analysis.
- Clinical presentation of a persistent ulcerated eyelid lesion.
- Serologic confirmation of Mpox infection.
- Antiviral therapy and symptom resolution.
Main Results:
- An HIV-positive patient presented with a large, atypical, plaque-like eyelid lesion refractory to initial treatments.
- Serologic testing confirmed Mpox infection.
- Antiviral therapy led to symptom resolution.
Conclusions:
- Mpox should be considered in the differential diagnosis of atypical periorbital lesions, particularly in HIV-positive individuals.
- Awareness of Mpox is crucial to avoid diagnostic delays caused by focusing solely on opportunistic infections in HIV patients.
