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Updated: Jun 5, 2025

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Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
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A nonlinear relationship between alcohol consumption and cognitive function in elderly people: a population-based
Kaiqi Chen1, Yunhua Li2, Rui Yue3
1School of Basic Medical, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Frontiers in Aging Neuroscience
|December 10, 2024
Summary
Higher alcohol intake is linked to poorer cognitive function in older Americans. This relationship is complex, varying by individual factors like gender and education.
Area of Science:
- Gerontology
- Neuroscience
- Public Health
Background:
- Cognitive decline is a significant concern in aging populations.
- The impact of alcohol consumption on cognitive function in the elderly requires further investigation.
Purpose of the Study:
- To examine the association between alcohol intake and cognitive function in elderly Americans.
- To explore potential nonlinear relationships and subgroup interactions.
Main Methods:
- Analysis of National Health and Nutrition Examination Survey (NHANES) data (2011-2014).
- Inclusion of 2,675 Americans aged 60+.
- Multivariate regression, smooth curve fitting, threshold effect analysis, and subgroup analyses were performed.
Main Results:
- A significant negative correlation was found between alcohol intake and cognitive function.
- Heavy drinkers showed reduced scores in word recall tests compared to non-heavy drinkers.
- Nonlinear relationships were identified with specific breakpoints for different cognitive tests.
Conclusions:
- Alcohol intake negatively impacts cognitive function in the elderly.
- The relationship is complex and moderated by factors such as gender, education, and smoking status.
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