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Loss of empathy in stroke
Wai Kwong Tang1, Edward Hui1,2, Thomas Wai Hong Leung3
1Department of Psychiatry, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Frontiers in Psychology
|December 10, 2024
Summary
Loss of empathy (LoE) after stroke impacts carers and is often missed. This study explores LoE
Area of Science:
- Neurology
- Neuropsychology
- Neuroimaging
Background:
- Loss of empathy (LoE) is prevalent in stroke survivors, leading to relationship strain and reduced quality of life for carers.
- LoE often remains undiagnosed and untreated, highlighting a critical gap in stroke care.
- Understanding LoE's impact is crucial for improving patient and carer outcomes.
Purpose of the Study:
- To evaluate the clinical and MRI correlates of LoE in stroke survivors.
- To describe the 12-month clinical course of LoE.
- To identify predictors of LoE remission.
Main Methods:
- Prospective cohort study of 246 stroke survivors and their carers.
- Assessments at 3, 9, and 15 months post-stroke using the Chinese Interpersonal Reactivity Index (IRI) for LoE.
- MRI, including diffusion-weighted imaging (DWI), to correlate lesions with LoE.
Main Results:
- This study is the first longitudinal investigation of LoE in stroke survivors.
- It will elucidate the association between prefrontal cortex/subcortical lesions and LoE risk, severity, and outcomes.
- Findings will advance understanding of LoE pathogenesis and clinical course in neurological conditions.
Conclusions:
- This research provides critical insights into the clinical and neuroanatomical underpinnings of LoE post-stroke.
- The findings are expected to inform clinical practice and stimulate further research in LoE.
- Understanding LoE is vital for improving the lives of stroke survivors and their families.
