Study of Conduction Blocks in ST Elevation Myocardial Infarction – A Cross-Sectional Analysis
Swapnil Shinde1, Nitin Jadhav1
1Department of General Medicine, Krishna Institute of Medical Sciences University, Maharashtra, India.
Insights
Conduction blocks after ST-elevation myocardial infarction (STEMI) increase patient risk. Complete heart block in STEMI patients is linked to higher mortality, indicating block severity predicts poor outcomes.
Area of Science:
- Cardiology
- Electrophysiology
- Internal Medicine
Background:
- Conduction blocks complicating ST-elevation myocardial infarction (STEMI) are associated with increased morbidity and mortality.
- Previous research on anterior and inferior wall myocardial infarction as causes of blocks yielded conflicting results.
- Patterns of conduction blocks and their prognostic implications in specific populations remain under-established.
Purpose of the Study:
- To investigate the diverse patterns of conduction blocks following ST-elevation myocardial infarction.
- To determine the prognostic significance of these conduction blocks in STEMI patients.
- To establish the prevalence and outcomes associated with different types of conduction blocks in a defined patient cohort.
Main Methods:
- Prospective study including 70 adult patients diagnosed with STEMI.
- Continuous observation for conduction blocks via standard 12-lead electrocardiograms every 48 hours post-ICU admission.
- Statistical analysis using R software (version 3.6.0) to assess block patterns and outcomes.
Main Results:
- The most common blocks were first-degree (28.6%), Mobitz II (20%), and complete heart block (17.1%).
- Mortality was significantly higher in patients with complete heart block (11.4%) and first-degree heart block (2.8%) (P = .003).
- No significant differences were found in block prevalence between males and females, nor in relation to cardiac enzymes, blood sugar, or lipid levels.
Conclusions:
- Complete heart block in STEMI patients is a significant predictor of poor prognosis and increased mortality.
- The severity of conduction block is a critical factor influencing outcomes in STEMI.
- Understanding conduction block patterns is crucial for risk stratification and management of STEMI patients.
Abstract:
Conduction blocks complicating ST(ST-segment)-elevation myocardial infarction are associated with increased morbidity and mortality. Research indicates that anterior and inferior wall myocardial infarction were the most encountered causes of blocks but with conflicting results. However, patterns of conduction blocks have not been widely established in our population. The aim was to study the various patterns of conduction blocks following ST-elevation myocardial infarction and their prognostic implications. Prospectively, 70 patients, aged > 18 years, diagnosed with ST segment elevation myocardial infarction were included in the study. Post intensive care unit admission, all patients were observed for conduction blocks using a standard 12-lead electrocardiogram and repeated the same every 48 h throughout the hospitalization stay. Statistical analysis was performed using software R version 3.6.0. Out of 70 patients, 70% were males. Mean age was 60.7 ± 13.4 years. The proportion of blocks was first-degree heart block (28.6%), Mobitz II heart block (20%), complete heart block (17.1%), Mobitz I heart block (11.4%), right bundle branch block (10%), left bundle branch block (10%), left anterior hemiblock (1.4%), and trifascicular block (1.4%). No significant diference was found between males and females with respect to various conduction heart blocks (P > .05). Mortality was observed only in patients with complete heart block (11.4%) and first-degree heart block (2.8%; P = .003). Statistically, no significant diference was observed between various conduction blocks with respect to cardiac enzymes, random blood sugar, and lipid levels (P > .05). High mortality rate has been found in the patients with complete heart block indicating that severity of conduction block is a predictor of poor outcome in the ST-elevation myocardial infarction patients.
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