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Intraoperative Burst Suppression Research: Quo Vadis?

Matthias Kreuzer1, Jamie W Sleigh2

  • 1Department of Anesthesiology and Intensive Care, School of Medicine and Health, Technical University of Munich, Munich, Germany.

Anesthesiology
|December 10, 2024
PubMed
Summary

No abstract available in PubMed .

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Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
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