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Association between urgency urinary incontinence and cause-specific mortality: a population-based analysis.

Sung Jin Kim1,2, Sung Gon Park1, Sahyun Pak1

  • 1Department of Urology, Hallym University Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea.

World Journal of Urology
|December 10, 2024
PubMed
Summary

Urgency urinary incontinence (UUI) is linked to a higher risk of death, including from cardiovascular disease and cancer. This study highlights UUI as a significant health concern impacting overall mortality across all demographics.

Keywords:
Lower urinary tract symptomsMortalityNutrition surveysUrinary bladderUrinary incontinence

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Area of Science:

  • Urology
  • Public Health
  • Epidemiology

Background:

  • Urgency urinary incontinence (UUI) affects many individuals, impacting quality of life.
  • Previous research on UUI's association with mortality is limited.

Purpose of the Study:

  • To investigate the relationship between UUI and cause-specific mortality.
  • To analyze mortality risks associated with UUI in a representative U.S. population.

Main Methods:

  • Utilized NHANES data (2005-2014) linked with the National Death Index (NDI) through December 2019.
  • Included 21,973 participants; UUI defined as involuntary urination within a year.
  • Employed Cox regression analysis to determine adjusted hazard ratios for mortality.

Main Results:

  • 21.8% of participants reported UUI.
  • UUI was associated with an elevated overall mortality risk.
  • Increased risk observed for cardiovascular disease, cancer, and other causes of death.

Conclusions:

  • UUI is a significant health burden associated with increased overall mortality.
  • Findings indicate a link between UUI and deaths from cardiovascular disease and cancer.
  • Further research into the causal relationship between UUI and mortality is warranted.