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Cross-species real-time detection of trends in pupil size fluctuation

  • 0Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), NIHBC 10 - Clinical Center BG RM 1D80, 10 Center Dr., Bethesda, MD, 20892, USA. sharif.kronemer@nih.gov.
Behavior Research Methods +

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December 10, 2024

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December 10, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

We developed rtPupilPhase, open-source software for real-time pupil size monitoring. This tool enables new research applications by automatically detecting trends in pupil size fluctuations.

Area Of Science

  • Neuroscience
  • Physiology
  • Psychology

Background

  • Pupillometry measures pupil size, reflecting neural activity in behavior, cognition, emotion, and perception.
  • Current methods lack real-time monitoring of pupil size fluctuations.

Purpose Of The Study

  • Introduce rtPupilPhase, an open-source software for real-time pupil size trend detection.
  • Enable novel applications in real-time pupillometry for research and translational goals.

Main Methods

  • Developed rtPupilPhase software for automatic, real-time detection of pupil size trends.
  • Validated the software's performance using human, rodent, and monkey pupil data.

Main Results

  • rtPupilPhase successfully detects trends in pupil size fluctuations in real time.
  • Demonstrated the software's efficacy across multiple species.

Conclusions

  • rtPupilPhase offers a novel tool for advancing real-time pupillometry research.
  • Future implementations can expand the utility of real-time pupillometry in various scientific fields.

Keywords: