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Mediators of Filgotinib Treatment Effects in Ulcerative Colitis: Exploring Circulating Biomarkers in the Phase 2b/3

Hiroshi Nakase1, Silvio Danese2, Walter Reinisch3

  • 1Department of Gastroenterology and Hepatology, Sapporo Medical University School of Medicine, Sapporo, Japan.

Inflammatory Bowel Diseases
|December 10, 2024
PubMed
Summary

This study identified key circulating biomarkers for ulcerative colitis (UC) and found that filgotinib effectively reduced inflammatory markers, with early changes mediating clinical improvements in UC patients.

Keywords:
biomarkersfilgotinibulcerative colitis

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