Can simultaneous coronary and peripheral angiography alter the treatment planning in Fontaine stage IV peripheral
Kosar Vaezzadeh1, Pouya Tayebi1, Seyed Farzad Jalali2
1Department of Vascular and Endovascular Surgery, Rouhani Hospital, Babol University of Medical Science, Babol, Iran.
Insights
Patients with advanced peripheral arterial disease (PAD) often have undetected coronary artery disease (CAD). Early coronary evaluation is crucial to prevent serious complications after peripheral revascularization.
Area of Science:
- Cardiovascular Medicine
- Vascular Surgery
- Interventional Cardiology
Background:
- Peripheral arterial disease (PAD) and coronary artery disease (CAD) are leading causes of mortality.
- Asymptomatic CAD is common in PAD patients, posing risks post-revascularization.
- Increased cardiac demand after peripheral revascularization can precipitate cardiac events in undiagnosed CAD.
Purpose of the Study:
- To determine the prevalence of coronary artery stenosis in patients with Fontaine Stage IV PAD.
- To analyze the correlation between the extent of peripheral and coronary artery disease.
- To underscore the importance of screening for CAD in this high-risk population.
Main Methods:
- Cross-sectional descriptive study of 60 patients with Fontaine Stage IV PAD.
- Simultaneous angiography of coronary and lower extremity arteries.
- Rigorous evaluation of arterial stenosis severity and correlation analysis.
Main Results:
- 51.7% of patients had significant three-vessel coronary artery disease.
- Severe peripheral artery stenosis was common, especially in tibial arteries.
- The majority of patients required coronary revascularization (CABG: 40%, PCI: 35%).
Conclusions:
- Advanced PAD frequently coexists with silent, critical coronary artery disease.
- Comprehensive coronary evaluation is essential for patients with advanced lower limb ischemia.
- Addressing undiagnosed CAD can mitigate serious post-revascularization complications.
Abstract:
ObjectivesPeripheral arterial disease (PAD) and coronary artery disease (CAD) are major contributors to global morbidity and mortality. Many PAD patients remain asymptomatic for CAD, which often leads to undetected coronary artery involvement. This hidden coronary disease poses significant risks, particularly following peripheral revascularization, as increased cardiac demand can precipitate complications.MethodsThis cross-sectional descriptive study assessed the prevalence of coronary artery stenosis in patients with Fontaine Stage IV peripheral arterial disease. Simultaneous angiography of both the coronary and lower extremity arteries was performed, and the severity of arterial stenosis was rigorously evaluated. The correlation between the extent of peripheral and coronary artery disease was analyzed.ResultsA total of 60 patients (63.3% male, 36.7% female; mean age 65.23 ± 9.86 years) were included. Comorbidities were common, with 90% having diabetes, 50% hypertension, 23.3% hyperlipidemia, and 30% smoking history. Severe peripheral artery stenosis was frequently observed, particularly in the posterior tibial artery (total occlusion in 26.6% and 20% of the right and left arteries, respectively). Significant coronary involvement was also prevalent, with 51.7% exhibiting three-vessel disease. Coronary revascularization was required in the majority of cases (CABG: 40%, PCI: 35%), with a higher proportion among women (77.2%) and men (73.7%).ConclusionThis study highlights the necessity of comprehensive coronary evaluation in patients with advanced lower limb ischemia. A substantial proportion of these patients have silent but critical coronary disease, which, if left unaddressed, could result in serious post-revascularization complications.
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