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Updated: Jul 15, 2026
05:07
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
534
Malperfusion, Malperfusion Syndrome, and Mesenteric Ischemia in Aortic Dissection
1Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Seminars in Thoracic and Cardiovascular Surgery
|December 10, 2024
Summary
Acute aortic dissection can cause malperfusion syndrome, leading to organ damage. Endovascular fenestration before central aortic repair may effectively treat this condition.
Area of Science:
- Cardiovascular Surgery
- Vascular Medicine
- Emergency Medicine
Background:
- Acute aortic dissection (AAD) frequently leads to aortic malperfusion.
- Malperfusion syndrome, characterized by end-organ ischemia, affects 10-33% of AAD patients.
- This condition poses a significant risk of rapid mortality.
Purpose of the Study:
- To review the incidence and management of aortic malperfusion in acute aortic dissection.
- To highlight the role of endovascular fenestration in treating malperfusion syndrome.
Main Methods:
- Literature review focusing on acute aortic dissection and malperfusion.
- Analysis of clinical presentations and treatment outcomes.
- Evaluation of endovascular fenestration as a therapeutic option.
Main Results:
- Aortic malperfusion is a common complication of acute aortic dissection.
- Malperfusion syndrome involves critical vascular territories including coronary, cerebral, visceral, and lower extremity arteries.
- Endovascular fenestration demonstrated effectiveness in managing malperfusion prior to definitive repair.
Conclusions:
- Malperfusion syndrome in acute aortic dissection is a life-threatening emergency.
- Prompt diagnosis and intervention are crucial for patient survival.
- Endovascular fenestration offers a viable treatment strategy for selected patients.
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