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Related Concept Videos

Exercise and Muscle Performance01:27

Exercise and Muscle Performance

1.3K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.3K

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Related Experiment Video

Updated: Jun 5, 2025

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
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Exercise as a Therapeutic Intervention in Multiple Sclerosis.

Lara A Pilutti1, Sarah J Donkers2

  • 1Interdisciplinary School of Health Sciences, University of Ottawa Brain and Mind Research Institute, University of Ottawa, Ottawa, ON, Canada.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|December 11, 2024
PubMed
Summary
This summary is machine-generated.

Exercise is increasingly recognized as a therapy for multiple sclerosis (MS), moving from symptom management to exploring disease-modifying potential. Further research is needed to optimize exercise prescriptions and improve access for all individuals with MS.

Keywords:
exercisefitnessmultiple sclerosisrehabilitationsymptomatic treatment

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Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Exercise Science

Background:

  • Historically, exercise participation for individuals with multiple sclerosis (MS) was discouraged.
  • Evolving evidence has shifted the paradigm, promoting exercise as a key therapeutic strategy for managing MS symptoms.
  • Current research is exploring the nascent potential of exercise to modify disease progression in MS.

Purpose of the Study:

  • To review the current evidence on exercise as a therapeutic intervention for multiple sclerosis (MS).
  • To summarize the evolving role of exercise, from symptom management to potential disease modification in MS.
  • To identify knowledge and implementation gaps and suggest future research directions.

Main Methods:

  • Topical review based on an invited presentation at the ACTRIMS Forum 2024.
  • Synthesis of existing scientific literature on exercise interventions in multiple sclerosis.
  • Analysis of current evidence regarding symptomatic and disease-modifying effects of exercise.

Main Results:

  • Exercise has transitioned from a cautioned activity to a recognized therapy for MS symptom management.
  • Emerging research suggests exercise may have disease-modifying effects in MS, though this area requires further investigation.
  • Significant gaps in knowledge and practical implementation hinder widespread accessibility of exercise as therapy for MS.

Conclusions:

  • Exercise plays a crucial, evolving role in managing multiple sclerosis.
  • Further research is essential to understand exercise's disease-modifying potential and optimize its application in MS.
  • Addressing implementation gaps is critical to ensure equitable access to exercise-based therapies for all individuals with MS.