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Updated: Jun 5, 2025
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Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
455
Using High-Speed Videoendoscopy to Analyze Laryngeal Closure Parameters During Normal Swallow
Rebecca J Howell1, Amna S Mira1,2,3, Andres Llico4
1Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio, U.S.A.
The Laryngoscope
|December 11, 2024
Summary
This pilot study found that a lower endoscope position and custom MATLAB GUI were well-tolerated for analyzing laryngeal high-speed videoendoscopy during swallowing. The novel method provides enhanced temporal resolution for laryngeal movement analysis.
Area of Science:
- Otolaryngology
- Swallowing Physiology
- Medical Imaging
Background:
- Standard laryngoscopy lacks the temporal resolution to fully analyze laryngeal dynamics during swallowing.
- High-speed videoendoscopy (HSV) offers improved frame rates but requires advanced analysis techniques.
- Custom software can enhance the visualization and quantification of laryngeal movements.
Purpose of the Study:
- To assess the tolerability of a lower endoscope position for laryngeal HSV.
- To evaluate the feasibility of a custom MATLAB graphical user interface (GUI) for analyzing laryngeal HSV during dry swallows.
- To determine if this method provides improved temporal resolution for glottic closure and laryngeal movement analysis compared to standard methods.
Main Methods:
- 14 healthy adults underwent laryngeal HSV at 500 frames per second (fps).
- A custom MATLAB GUI was developed to analyze the swallowing segment of interest (SOI).
- Feasibility, tolerability, and the ability to identify and sequence laryngeal movements were assessed.
Main Results:
- The procedure was well-tolerated by all participants.
- The custom GUI enabled analysis of 130 frames within the SOI (mean 260 ms), significantly more than standard laryngoscopy (7 frames).
- Vocal fold adduction, medialization, and arytenoid compression were identifiable and could be sequenced.
Conclusions:
- A lower endoscope position and custom GUI are feasible and well-tolerated for analyzing laryngeal HSV during dry swallows.
- This novel technique enhances the identification, description, and sequencing of laryngeal swallowing events.
- Further research with bolus, diverse populations, and pathological conditions is warranted to understand swallowing physiology better.
