Outcome reporting in studies on critically ill obstetric patients: A systematic review
Julien Viau-Lapointe1, Julia Kfouri2, Mary Thompson3,4
1Department of Medicine, Hôpital Maisonneuve-Rosemont, Université de Montréal, Montreal, Canada.
Introduction:
This systematic review is the first step in the process of standardizing outcome reporting through the development of a core outcome set for research on critically ill obstetric patients (COSCO).
Methods:
A five-database search was performed to identify randomized and non-randomized studies published before November 2017, on patients admitted to intensive care or high-dependency units during or immediately after pregnancy. Reported outcomes were categorized into domains and definitions were documented.
Results:
Of the 12,581 citations reviewed, 136 studies were included. The most reported outcome domains were maternal all-cause mortality (n = 128, 94.5%), resource use (n = 116, 85.6%), and clinical/physiological outcomes (n = 111, 82.8%). Outcomes related to functioning/life impact and adverse effects of treatment were only reported in four (2.9%) studies. There was inconsistency in outcome definitions.
Conclusions:
This review identified considerable variation in outcome reporting and definitions and generated an outcome list to consider in COSCO development.
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